Mixed-mode weak cation exchange columns for strong basic analyte extraction
- High surface area and capacity ensure highly reliable retention characteristics
- No secondary interactions from silanol groups for accurate results
- Higher sample loading due to high surface area
Recover clean extracts and shorten the time spent on method development using TELOS neo WCX SPE columns. Columns contain a mixed-mode weak cation exchange sorbent containing nonpolar and weak acid functional groups. This dual retention mechanism provides an ideal environment for successful retention and elution of all basic compounds, including strong bases and quaternary amines.
High surface area and capacity allow the use of smaller sorbent masses, leading to reduced elution volumes and evaporation/reconstitution steps. Polymeric sorbents are water-wettable and not affected by drying out, providing better flow characteristics, retention, and elution.