Signal Transduction Products (0)

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  • Thumbnail Image for Biomol Green Reagent

    Enzo Life Sciences

    The BIOMOL GREEN™ Reagent is a convenient, 1-step reagent for measuring the free phosphate released during enzymatic phosphatase assays. It is a modification of the classic Malachite green reagent 1,2 and it offers the following advantages: Non-Radioactive Convenient one-step reagent: No...

  • Thumbnail Image for Sulfurhodamine Multi-Caspase Activity Kit

    Enzo Life Sciences

    The Sulforhodamine Multi-Caspase Activity Kit detects active caspase enzymes in living cells. Sulforhodamine (SR) labeled caspase inhibitor probes bind to active caspase enzymes in living cell systems. These inhibitors are both cell-permeable and non-cytotoxic during the time of the labeling...

  • Thumbnail Image for Rapamycin

    Enzo Life Sciences

    98%, MW=914.2 [53123-88-9] Storage: -20°C Rapamycin is one member of a family of macrolide immunosuppressants which bind to and inhibit the FK506 binding protein (FKBP) proline rotamase 1 . Rapamycin is bound simultaneously by FKBP12 and FRAP (FKBP12-Rapamycin-Associated-Protein) 2 . FRAP...

  • Thumbnail Image for Ubiquitinylation (Ubiquitin Conjugation) Kit, 50 Assays

    Enzo Life Sciences

    Store at -80°C This kit provides the means of generating a range of thioester-linked ubiquitin conjugation enzymes (E2s), utilizing the first two steps in the ubiquitin cascade; for use in the transfer of ubiquitin to E3 ligases; and the subsequent ubiquitinylation of target substrate proteins....

  • Thumbnail Image for MMP-12 Fluorescent Assay Kit, For Drug Discovery

    Enzo Life Sciences

    A QuantiZyme™ Assay System. The MMP-12 Fluorescent Assay Kit for Drug Discovery is a complete assay system designed to measure protease activity of matrix metalloproteinase-12 (MMP-12, metalloelastase, macrophage elastase) using a quenched fluorescent peptide: OmniMMP™ fluorescent...

  • Thumbnail Image for RII Phosphopeptide, Calcineurin Substrate, 500 ug

    Enzo Life Sciences

    Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-pSer-Val-Ala-Ala-Glu >97%, MW=2192.0, Storage: -20°C Sequence is from cAMP-dependent protein kinase (PKA) regulatory subunit type II (RII), but with a phosphoserine at Ser-95. This peptide can be used directly as a calcineurin (protein...

  • Thumbnail Image for HDAC Fluorimetric Assay / Drug Discovery Kit  -  A F

    Enzo Life Sciences

    No Radioactivity No Extractions HTS Friendly-Mix and Read on One 96-well Plate For Class I and Class II HDACs and Sirtuins Applications Include Cell-Based Assays and Assay of Immunoprecipitates Histone deacetylase inhibitors have shown promise as anti-tumor agents and naturally this has stimulated...

  • Thumbnail Image for IR5 Insulin Receptor, 0.5 mg

    Enzo Life Sciences

    Thr-Arg-Asp-Ile-pTyr-Glu-Thr-Asp-Tyr-Tyr-Arg-Lys >97%, MW=1703.0, Storage: -20°C Phosphopeptide corresponding to the insulin receptor regulatory region. Can be used as a tyrosine phosphatase substrate 1 . 1. H. Cho et al., "Prot. Science" 1993, 2: 977

  • Thumbnail Image for Caspase-4, 5000 U

    Enzo Life Sciences

    >90% by SDS-PAGE, MW=19 + 10 kDa Storage: -80°C Highly active caspase-4 (Ich-2, TX, ICErel-II), from human cDNA, expressed in an E.coli expression system. cDNA encodes residues identical to Ala-105 to Asn-377 (C-term) at genbank accession # NP-001216. Used to study enzyme regulation and...

  • Thumbnail Image for Caspase-9, Caspase-9 Full Length

    Enzo Life Sciences

    >95% by SDS-PAGE, MW=20 + 12 kDa Storage: -80°C Caspase-9 is the initiator caspase of the mitochondrial/Apaf-1 apoptosis induction pathway 3-6 . This active caspase-9 (ICE-LAP-6; Mch6) is made from a human cDNA, expressed in E. coli. cDNA encodes residues identical to Ile-131 to Ser-416...

  • Thumbnail Image for Caspase-7, 5000 U

    Enzo Life Sciences

    >95% by SDS-PAGE, MW=20 + 12 kDa Storage: -80°C Caspase -7 1,2 is an effector caspase 3,4 in apoptosis with similar substrate preferences to caspase-3. Like caspase-3, it can cleave PARP-1 5-7 . It displays an affinity for ADP-ribose polymers and automodification of PARP-1 (ADP-ribosylation)...

  • Thumbnail Image for IR0 Insulin Receptor, 0.5 mg

    Enzo Life Sciences

    Thr-Arg-Asp-Ile-Tyr-Glu-Thr-Asp-Tyr-Tyr-Arg-Lys >97%, MW=1622.9, Storage: -20°C Sequence is from insulin receptor β -subunit cytoplasmic domain, inclusive of regulatory autophosphorylation sites Tyr 1146, 1150 and 1151 1 . It has been used as an insulin receptor tyrosine kinase substrate...

  • Thumbnail Image for Caspase-3 Cellular Assay Kit PLUS  -  A Quantizyme

    Enzo Life Sciences

    This kit is a complete assay system for measuring caspase-3 and caspase-3-like activity (DEVDase) in cellular extracts. It includes both colorimetric and fluorogenic substrates. It is performed in a convenient 96-well format with all reagents necessary for preparing cell extracts, measuring caspase...

  • Thumbnail Image for Calcineurin Colorimetric Drug Discovery Kit  -  A

    Enzo Life Sciences

    Non-Radioactive Convenient 1-Step Detection: No mixing Microtiter Plate Format: For high-throughput This colorimetric assay kit is useful for measuring calcineurin (PP2B) phosphatase activity of purified enzyme and for screening inhibitors. The assay is performed in a convenient 96-well plate...

  • Thumbnail Image for 5-Iodotubercidin

    Enzo Life Sciences

    98%, MW=392.2 [24386-93-4] Storage:-20°C Inhibits ERK2 (Ki= 525nM) 1 . also inhibits adenosine kinase (Ki= 30nM) CK1 and CK2 and insulin receptor kinase 2 . 1. T. Fox et al, "Protein Sci." 1998, 7: 2249 2. D. Massillon et al., "Biochem. J." 1994, 299: 123

  • Thumbnail Image for GO 6983

    Enzo Life Sciences

    95%, MW=442.5, Storage: -20°C PKC inhibitor. Has been shown to selectively inhibit several PKC isoenzymes (IC50= 7nM for PKCα and PKCβ ; 6nM for PKCγ ; 10nM for PKCδ ; 60nM for PKCζ ). The compound does not effectively inhibit PKCµ (IC50=...

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